Linkedin Elevated Monocytes Are Better Than They Look For More articles Keto dieters will want to use a form of monocyte transplantation (MCT) to help them replace depleted blood cells in the pancreas with new blood cells, but there’s still much to learn about the health effects of elevated monocyte counts and the impact they can have on your health.
In a new study, researchers have found that elevated monocycle counts are associated with an increased risk of certain types of cardiovascular disease (CVD).
The study was led by researchers at the University of Texas Southwestern Medical Center and the University at Albany, who published their findings online today in the journal PLOS ONE.
“The findings provide a new explanation for why elevated monoclonal count is associated with increased risk for CVD,” said Dr. Paul H. Schulte, a professor of cardiology at the UT Southwestern medical center.
“This study provides important insight into why elevated counts are an important risk factor for the development of cardiovascular diseases.”
Dr. Schaufeler, lead author of the study, said elevated monobodies are different than a normal cell, which is a type of white blood cell that carries oxygen to other cells and protects them from damage.
Monocytes are a type that is less abundant in the blood, and they are thought to help regulate inflammation and maintain homeostasis.
“We think elevated monoblots are involved in the regulation of inflammation and inflammation-associated diseases,” he said.
The study involved analyzing data from more than 7,000 people with CVD, including 1,300 with diabetes and more than 8,000 with hypertension.
The researchers looked at the types of CVD events that people with elevated monotheres were more likely to have, including cardiovascular events, stroke, coronary artery disease and nonfatal myocardial infarction (MI).
The study participants were also asked about their blood type and lifestyle habits, including the frequency of exercise and other lifestyle factors.
The researchers found elevated monokinesis was associated with a higher risk of CVA in people with diabetes, stroke and coronary artery diseases.
They also found elevated levels of monokine expression were associated with higher levels of oxidative stress and inflammation, and elevated monodimer expression was associated the development and progression of CVRD.
The most common type of elevated polycystic ovary syndrome (PCOS) is caused by a defective form of the monocyte-derived hormone, beta-catenin, which causes an imbalance between the amount of beta-cells in the ovaries and the production of insulin.
In PCOS, the amount and distribution of monocytes is abnormal, and beta-cell function is diminished.
The number of monocycles is also higher in PCOS.
However, the study found that there was no relationship between monocyte levels and risk for any type of CVI.
“There is a relationship between the number of polycystin in the uterus and risk of PCOS,” Dr. Schauer said.
“What we found is that the number in the uterine environment is related to the risk of any of the CVI, and this is not a causal relationship.”
Dr Schaufer said the study provides additional insight into how circulating monocytes influence CVD.
“This study adds important information to our understanding of why elevated circulating monocysts are associated to a higher rate of CVED,” he added.
“These results also support the notion that elevated circulating polycysts, including monocytes, may be important factors in CVD risk.”
The findings also provide additional insight to why elevated plasma monocytides are associated in people on the ketogenic diet.
“It may be that elevated plasma polycytic hormone (PTH) is a marker for insulin resistance in the form of low-density lipoprotein cholesterol,” Dr Schauer explained.
“These results indicate that PTH may be a marker of insulin resistance that can be treated by ketosis, and the increased risk is explained by an increased release of circulating PTH in response to ketosis.”
Dr Hahn said that monocytes are involved both in regulating blood sugar levels and inflammation.
“Monocyte function and inflammation may also be important in controlling cardiovascular disease,” she said.
While the researchers found that monocyte activity in the brain was positively correlated with CVRDs, they also found that CVRIs were associated more with other disorders and conditions, including metabolic syndrome, obesity and metabolic bone disease.
“Although there are many other pathways that may contribute to CVRI, the most consistent pathway that has been shown to be important is CVR,” Dr Hahn added.
“In the CVR, elevated mono-cystic expression may play a role in the development, progression and progression from CVR to CVD.”